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The biopharmaceutical industry requires materials that have excellent properties for the processing of specialty chemicals, high purity water, and resistance to various methods of sterilization required in the processing of pharmaceuticals. Select Kynar® grades meet the extreme demands and regulatory requirements of this growing industry.

Product Overview: Kynar® PVDF

For Biopharmaceutical applications requiring excellent resistance to acids, chlorine and bromine, Kynar® PVDF is a commonly used material of construction for process piping, pumps, tubing, tanks, filters and other fluid handling components. In addition to the chemical resistance of the process stream, Kynar® PVDF is also resistant to many common forms of sterilization such as ozonation, chemical bleaching, and steam-cleaning.

Common Kynar® PVDF Applications


Instead of:

Up to:


Exposure to chlorinated & brominated chemicals

Titanium alloy 20


PTFE-lined steel


PFA-lined steel

275°F (135°C)

Lower cost


Easier installation


Lower permeation

Exposure to hot acids (eg: HF, HCl, H2SO4, HNO3, chromic, HBr)



alloy 20


PTFE-lined steel

275°F (135°C)

Lower cost


Easier installation


Chemical resistance at varied concentrations

Alcohol + acids /chlorides /hydrocarbons




194°F (90°C)

Broad chemical resistance at varied concentrations

High pressure + high temperature






285°F (141°C) and 340 psi at RT

High temperature Rigidity


High pressure rating


Broad chemical resistance

Easy Processing for a Complete Solution

The thermoplastic Kynar® PVDF family of resins is characterized by ease of welding and post forming. As Kynar® PVDF has a wide window of processing between the melting point and the onset of decomposition, it is commonly welded by several methods: butt fusion, socket fusion, electrofusion, bead and crevice free, hot gas welding, extrusion welding, ultra-sonic welding, and hot lamination. Alternatively, Kynar® PVDF can also be mechanically joined.  This ease of fabrication enables multiple piping system joining methods, construction of tanks and vessels, and specialty fluid handling components. In addition, Kynar® PVDF and Kynar Flex® PVDF give the designer the ability to confidently join rigid and flexible fluoropolymers in the same construction

Select grades of Kynar® PVDF are carefuly designed with attention to molecular weight distribution and melt flow rate to allow the fabricators who injection mold and extrude to produce parts with very smooth surfaces. In the biopharmaceutical industry this feature is important as it leads to fewer crevices and pores that could harbor the growth of bacteria. 

Surface Comparison After Two Years of Operation


Notes: 63 mm pipe (2 1/2"); 1.5m/sec velocity or purified water; sanitized nightly (30 PPM ozone); 2 years of service

Industry Specification Conformity

Select Kynar® PVDF and Kynar Flex® PVDF resins are tested in compliance with Title 21, Code of Federal Regulations, Chapter 1, Part 177.2510 or 177.2600, USP Class VI, NSF 51 & NSF 61, listed in ASME BPE,  Kosher certification by the Chicago Rabbinical Council (CRC), and Halal certified.

Sterilization Techniques

Kynar® PVDF resin can be sterilized by most techniques including: steam sterilization, gamma radiation, ethylene oxide (EtO), autoclave, ozone, and other various chemical methods, such as bleach and peroxides.